A non-targeted LC-MS metabolic profiling of pregnancy: longitudinal evidence from healthy and pre-eclamptic pregnancies.
Tiina J JääskeläinenOlli KärkkäinenJenna JokkalaAnton KlåvusSeppo HeinonenSeppo AuriolaMarko Lehtonennull nullKati HanhinevaHannele LaivuoriPublished in: Metabolomics : Official journal of the Metabolomic Society (2021)
Our study highlights the need of large-scale longitudinal metabolomic studies in non-complicated pregnancies before more detailed understanding of metabolism in adverse outcomes could be provided. Our findings are one of the first steps for a broader metabolic understanding of the physiological changes caused by pregnancy per se.