Sex-specific microRNA expression networks in an acute mouse model of ozone-induced lung inflammation.
Nathalie FuentesArpan RoyVikas MishraNoe CabelloPatricia SilveyraPublished in: Biology of sex differences (2018)
Our results indicate that both sex and hormonal status can influence lung miRNA expression in response to ozone exposure, indicating that sex-specific miRNA regulation of inflammatory gene expression could mediate differential pollution-induced health outcomes in men and women.
Keyphrases
- gene expression
- poor prognosis
- mouse model
- particulate matter
- oxidative stress
- diabetic rats
- drug induced
- high glucose
- hydrogen peroxide
- dna methylation
- risk assessment
- heavy metals
- liver failure
- binding protein
- long non coding rna
- air pollution
- type diabetes
- adipose tissue
- metabolic syndrome
- health risk assessment
- insulin resistance
- extracorporeal membrane oxygenation