Synaptic Plasticity of Human Umbilical Cord Mesenchymal Stem Cell Differentiating into Neuron-like Cells In Vitro Induced by Edaravone.

Yunpeng ShiChengrui NanZhongjie YanLiqiang LiuJingjing ZhouZongmao Zhao De-Pei Li

Published in: Stem cells international (2018)

Edaravone can dose-dependently induce hUMSCs to differentiate into neuron-like cells that expressed the neuronal markers including NSE, nestin, and GFAP and synaptic makers such as SYN, PSD95, and GAP43.

Keyphrases

umbilical cord
mesenchymal stem cells
endothelial cells
bone marrow
cell therapy
induced pluripotent stem cells
pluripotent stem cells
cerebral ischemia
stem cells
computed tomography
magnetic resonance
subarachnoid hemorrhage