Effect of a day-trip to altitude (2500 m) on exercise performance in pulmonary hypertension: randomised crossover trial.
Simon R SchneiderLaura C MayerMona LichtblauCharlotte BerlierEsther I SchwarzStéphanie SaxerLu TanMichael FurianKonrad E BlochStéphanie SaxerPublished in: ERJ open research (2021)
This randomised crossover study showed that the majority of PH patients tolerate a day-trip to 2500 m well. At high versus low altitude, the mean exercise time was reduced, albeit with a high interindividual variability, and pulmonary artery pressure at rest and during exercise increased, but pressure-flow slope and dyspnoea were unchanged.
Keyphrases
- pulmonary artery
- pulmonary hypertension
- clinical trial
- open label
- high intensity
- coronary artery
- study protocol
- pulmonary arterial hypertension
- double blind
- end stage renal disease
- physical activity
- placebo controlled
- phase iii
- phase ii
- resistance training
- ejection fraction
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- randomized controlled trial