IL-6 variant is associated with metastasis in breast cancer patients.
Chike O AbanaBrian S BinghamJu Hwan ChoAmy J GravesTatsuki KoyamaRobert T PilarskiA Bapsi ChakravarthyFen XiaPublished in: PloS one (2017)
These findings suggest that GG SNP at IL-6: rs1800795 may indicate an increased risk of metastasis of primary breast cancer. Further studies in larger population sets are warranted as advanced screening and prophylactic intervention might be employed in GG carriers.