BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD.
Uyen TranAndrew J StreetsDevon SmithEva DeckerAnnemarie KirschfinkLahoucine IzemJessie M HasseyBriana RutlandManoj K ValluruJan Hinrich BräsenElisabeth OttDaniel EptingTobias EisenbergerAlbert Cm OngCarsten BergmannOliver WesselyPublished in: bioRxiv : the preprint server for biology (2024)
variants may aggravate disease severity highlighting RNA metabolism as an important new concept for disease modification in ADPKD.