PD-1 mediates decidual γδ T cells cytotoxicity during recurrent pregnancy loss.

Rong GuoSilin JiangJianliang ZhangQuanli YangLiang GaoWei XiaLingxia TongPeiran FengYan XuTao ZhangHao ChengCuiPing LiuXueguang ZhangZhinan YinHong Zhang

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2022)

Our study uncovers an important role of PD-1 expression on decidual γδ T cells in maintaining the normal pregnancy, and may provide a new strategy for immune therapy against RPL.

Keyphrases

preterm birth
poor prognosis
pregnancy outcomes
stem cells
binding protein
pregnant women
long non coding rna
bone marrow
nk cells