What is the potential of paramagnetic rim lesions as diagnostic indicators in multiple sclerosis?
Maria Sofia MartireMoiola LMaria Assunta RoccaMassimo FilippiMartina AbsintaPublished in: Expert review of neurotherapeutics (2022)
Current research suggests that PRL can improve the diagnostic specificity and the overall accuracy of MS diagnosis when used together with the dissemination in space MRI criteria and the central vein sign. Nevertheless, future prospective multicenter studies should further define the real-world prevalence and specificity of PRL. International guidelines are needed to establish methodological criteria for PRL identification before its implementation into clinical practice.
Keyphrases
- multiple sclerosis
- clinical practice
- primary care
- mass spectrometry
- magnetic resonance imaging
- risk factors
- healthcare
- contrast enhanced
- structural basis
- white matter
- current status
- ms ms
- cross sectional
- clinical trial
- quality improvement
- magnetic resonance
- case control
- computed tomography
- double blind
- diffusion weighted imaging
- human health
- risk assessment