In vitro effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) on the expression of genes related to sperm motility and energy metabolism and intracytoplasmic sperm injection outcomes in obstructive azoospermic patients.
Samaneh AghajanpourElham HosseiniFatemeh Sadat AmjadiMasoud MohammadianZahra ZandiehFarnaz MohammadianRaheleh KafaeinezhadMahnaz AshrafiPublished in: Molecular biology reports (2024)
GM-CSF increased the expression of genes related to motility and the energy metabolism pathway and effectively promoted the motility of testis-extracted spermatozoa, consequently yielding positive clinical outcomes.
Keyphrases
- poor prognosis
- biofilm formation
- end stage renal disease
- genome wide
- ejection fraction
- newly diagnosed
- chronic kidney disease
- adipose tissue
- prognostic factors
- binding protein
- long non coding rna
- staphylococcus aureus
- type diabetes
- pseudomonas aeruginosa
- peripheral blood
- gene expression
- dna methylation
- escherichia coli
- cerebrospinal fluid
- candida albicans
- ultrasound guided
- genome wide analysis
- drug induced
- patient reported