Neoplastic and immune single cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma.

Kent A RiemondySujatha VenkataramanNicholas WillardAnandani NellanBridget SanfordAndrea M GriesingerVladimir AmaniSiddhartha MitraTodd C HankinsonMichael H HandlerMartin SillJennifer OcasioSeth J WeirDaniel S MalawskyTimothy R GershonAlexandra GarancherRobert J Wechsler-ReyaJay R HesselberthNicholas K ForemanAndrew M DonsonRajeev Vibhakar

Published in: Neuro-oncology (2021)

These findings provide a clearer understanding of the diverse neoplastic and immune cell subpopulations that constitute the MB microenvironment.

Keyphrases

single cell
rna seq
high throughput
stem cells
early life
randomized controlled trial
clinical trial