Effect of Recombinant Human Parathyroid Hormone (1-84) on Resolution of Active Charcot Neuro-osteoarthropathy in Diabetes: A Randomized, Double-Blind, Placebo-Controlled Study.

Nina L PetrovaNicholas K DonaldsonMaureen BatesWegin TangTimothy JemmottVictoria MorrisTracy DewLisa MeacockDavid A EliasCajetan F MonizMichael E Edmonds

Published in: Diabetes care (2021)

This double-blind placebo-controlled trial did not reduce time to resolution or enhance fracture healing of CN. There was no added benefit of daily intervention with PTH (1-84) to below-knee casting in achieving earlier resolution of CN.

Keyphrases

double blind
placebo controlled
recombinant human
clinical trial
single molecule
lymph node metastasis
phase iii
randomized controlled trial
study protocol
type diabetes
phase ii
cardiovascular disease
total knee arthroplasty
glycemic control
metabolic syndrome