A phase 2 study for evaluating doxycycline 50 mg once daily and 100 mg once daily as preemptive treatment for skin toxicity in patients with metastatic colorectal cancer treated with an anti-EGFR and chemotherapy.

Patricia Ramírez DaffósEncarnación Jiménez-OrozcoMatilde BolañosBeatriz González AstorgaSandra RubialesEduardo Ceballos-BarbanchoJosé Manuel Rodríguez GarcíaJuan-José Reina

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2022)

ClinicalTrials.gov NCT03448731.

Keyphrases

metastatic colorectal cancer
small cell lung cancer
physical activity
open label
epidermal growth factor receptor
oxidative stress
tyrosine kinase
soft tissue
squamous cell carcinoma
clinical trial
randomized controlled trial
radiation therapy
newly diagnosed
replacement therapy
placebo controlled