Blood and Site of Disease Inflammatory Profiles Differ in Patients With Pericardial Tuberculosis and Human Immunodeficiency Virus Type 1.

Hygon Mutavhatsindi Elsa Du BruynSheena RuzivePatrick Howlett Maddalena Cerrone Alan Sher Katrin D Mayer-Barber Daniel L Barber Mpiko Ntsekhe Robert John Wilkinson Catherine Riou

Published in: Open forum infectious diseases (2023)

Our results show that the inflammatory profile in blood was comparable between PTB and PCTB. However, at the site of infection (PCF), inflammation was significantly elevated compared to blood. Additionally, our data emphasize the potential role of HLA-DR expression as a biomarker for TB diagnosis.

Keyphrases

human immunodeficiency virus
oxidative stress
hepatitis c virus
mycobacterium tuberculosis
antiretroviral therapy
poor prognosis
hiv aids
hiv infected
machine learning
big data
hiv positive
risk assessment
climate change
human health
long non coding rna
binding protein
drug induced