Open-label randomized controlled trial of ultra-low tidal ventilation without extracorporeal circulation in patients with COVID-19 pneumonia and moderate to severe ARDS: study protocol for the VT4COVID trial.
Jean-Christophe RichardHodane YonisLaurent BitkerSylvain RocheFlorent WalletClaire DupuisHassan SerrierLaurent ArgaudGuillaume ThieryBertrand DelannoyChristian PommierPaul AbrahamMichel MullerFrederic AubrunFlorian SigaudGuillaume RigaultEmilie JoffredoMehdi MezidiNicolas TerziMuriel RabilloudPublished in: Trials (2021)
ClinicalTrials.gov NCT04349618 . Registered on April 16, 2020.
Keyphrases
- study protocol
- open label
- randomized controlled trial
- respiratory failure
- phase iii
- mechanical ventilation
- phase ii
- coronavirus disease
- extracorporeal membrane oxygenation
- sars cov
- acute respiratory distress syndrome
- clinical trial
- high intensity
- carbon dioxide
- phase ii study
- early onset
- high resolution
- intensive care unit
- double blind
- squamous cell carcinoma
- systematic review
- respiratory syndrome coronavirus
- placebo controlled
- drug induced
- mass spectrometry
- radiation therapy
- meta analyses