Efficacy of Curcumin on Treating Cancer Anorexia-Cachexia Syndrome in Locally or Advanced Head and Neck Cancer: A Double-Blind, Placebo-Controlled Randomised Phase IIa Trial (CurChexia).
Tawasapon ThambamroongKasan SeetalaromSiriwimon SaichaemchanYanisa PumsutasNaiyarat PrasongsookPublished in: Journal of nutrition and metabolism (2022)
The curcumin add-on resulted in a significant increase in muscle mass than standard nutritional support. Furthermore, it may improve and delay a decrease in the other body composition parameters, handgrip strength, and absolute lymphocyte count. Curcumin was safe and well tolerated. This constitutes an unmet need for clinical trials. This trial is registered with NCT04208334.
Keyphrases
- clinical trial
- body composition
- phase ii
- phase iii
- placebo controlled
- study protocol
- double blind
- open label
- resistance training
- papillary thyroid
- bone mineral density
- peripheral blood
- randomized controlled trial
- phase ii study
- case report
- squamous cell
- radiation therapy
- lymph node metastasis
- postmenopausal women
- rectal cancer