Adenosine-Prefabricated Adipose Tissue Improves Fat Graft Survival by Promoting VEGF-Dependent Angiogenesis.

Jiyeon ChangWoo Jin SongShindy SoedonoSharlene SharleneYeong Jin KimChang Yong ChoiKae Won Cho

Published in: Tissue engineering and regenerative medicine (2022)

Adenosine prefabrication in fat improved the graft survival by enhancing angiogenesis through the VEGF/VEGFR axis in the preadipocytes and endothelial cells. Therefore, this method may be used as a novel strategy to increase the retention rate in fat grafts.

Keyphrases

endothelial cells
adipose tissue
vascular endothelial growth factor
high glucose
insulin resistance
high fat diet
fatty acid
type diabetes
protein kinase
metabolic syndrome