Temporal trends in pulmonary arterial hypertension: Results from the COMPERA registry.
Marius M HoeperChristine PauschEkkehard GrünigGerd StaehlerDoerte HuscherDavid PittrowKaren M OlssonCarmine Dario VizzaHenning GallOliver DistlerChristian OpitzJ Simon R GibbsMarion DelcroixHossein Ardeschir GhofraniStephan RosenkranzDa-Hee ParkRalf EwertHarald KaemmererTobias J LangeHans-Joachim KabitzDirk SkowaschAndris SkrideMartin ClaussenJuergen BehrKatrin MilgerMichael HalankHeinrike WilkensHans-Jürgen SeyfarthMatthias HeldDaniel DumitrescuIraklis TsangarisAnton Vonk-NoordegraafStéphanie SaxerHans KlosePublished in: The European respiratory journal (2021)
The use of combination therapy increased from 2010 to 2019, but most patients still received monotherapy. Survival rates at 1 year after diagnosis did not change over time. Future studies need to determine if the observed trend suggesting improved 3-year survival rates can be confirmed.