Prehospital administration of broad-spectrum antibiotics for sepsis patients: A systematic review and meta-analysis.
Joseph VarneyKaram R MotaweaOmneya A KandilHashim Talib HashimKimberly MurryJaffer ShahAhmed ShaheenJoy AkwariAhmed Khaled AwadAmanda RiveraMostafa R MostafaSarya SwedDina M AwadPublished in: Health science reports (2022)
This meta-analysis reveals that receiving prehospital antibiotics can significantly lower mortality in sepsis patients compared to patients who do not receive prehospital antibiotics. However, more clinical trials and multicenter prospective studies with high sample sizes are needed to get strong evidence supporting our findings.
Keyphrases
- end stage renal disease
- clinical trial
- cardiac arrest
- systematic review
- ejection fraction
- newly diagnosed
- chronic kidney disease
- intensive care unit
- prognostic factors
- acute kidney injury
- peritoneal dialysis
- randomized controlled trial
- cardiovascular events
- septic shock
- meta analyses
- open label
- double blind
- phase iii
- placebo controlled