Candida and the Gram-positive trio: testing the vibe in the ICU patient microbiome using structural equation modelling of literature derived data.
James C HurleyPublished in: Emerging themes in epidemiology (2022)
GSEM modelling of published ICU infection prevention data enables the postulated interactions between Candida and Gram-positive bacteria to be tested using clinically derived data. The optimal model implies interactions occurring in the human microbiome facilitating bacterial invasion and infection. This interaction might also account for the paradoxically high bacteremia incidences among studies of TAP in ICU patients.
Keyphrases
- intensive care unit
- electronic health record
- gram negative
- big data
- mechanical ventilation
- end stage renal disease
- endothelial cells
- candida albicans
- newly diagnosed
- ejection fraction
- systematic review
- randomized controlled trial
- prognostic factors
- case report
- staphylococcus aureus
- meta analyses
- extracorporeal membrane oxygenation