Cryo-EM structure of the human Sirtuin 6-nucleosome complex.
Un Seng ChioOthman RechicheAlysia R BryllJiang ZhuJessica L FeldmanCraig L PetersonSong TanJean Paul ArmachePublished in: bioRxiv : the preprint server for biology (2023)
The structure of the SIRT6 deacetylase/nucleosome complex suggests how the enzyme acts on both histone H3 K9 and K56 residues.