Chlorthalidone for Hypertension in Advanced Chronic Kidney Disease.
Rajiv AgarwalArjun D SinhaAndrew E CramerMary Balmes-FenwickJazmyn H DickinsonFangqian OuyangWanzhu TuPublished in: The New England journal of medicine (2021)
Among patients with advanced chronic kidney disease and poorly controlled hypertension, chlorthalidone therapy improved blood-pressure control at 12 weeks as compared with placebo. (Funded by the National Heart, Lung, and Blood Institute and the Indiana Institute of Medical Research; CLICK ClinicalTrials.gov number, NCT02841280.).
Keyphrases
- blood pressure
- chronic kidney disease
- end stage renal disease
- hypertensive patients
- heart rate
- healthcare
- heart failure
- peritoneal dialysis
- blood glucose
- quality improvement
- randomized controlled trial
- type diabetes
- atrial fibrillation
- metabolic syndrome
- cell therapy
- stem cells
- insulin resistance
- skeletal muscle
- weight loss
- smoking cessation