Do comorbidities predict pain and function in knee osteoarthritis following an exercise intervention, and do they moderate the effect of exercise? Analyses of data from three randomized controlled trials.
Amardeep LeghaDanielle L BurkeNadine E FosterDanielle A van der WindtJonathan G QuickeEmma L HealeyJos RunhaarMelanie Ann HoldenPublished in: Musculoskeletal care (2019)
Obesity and anxiety/depression predicted pain and function outcomes in people offered an exercise intervention, but only the presence of cardiac problems might moderate the effect of exercise for knee OA. Further confirmatory investigations are required.
Keyphrases
- high intensity
- knee osteoarthritis
- randomized controlled trial
- resistance training
- physical activity
- chronic pain
- pain management
- metabolic syndrome
- type diabetes
- neuropathic pain
- insulin resistance
- mental health
- left ventricular
- clinical trial
- sleep quality
- spinal cord
- heart failure
- electronic health record
- body composition
- machine learning
- skeletal muscle
- high fat diet induced
- deep learning