Tracking longitudinal genetic changes of circulating tumor DNA (ctDNA) in advanced Lung adenocarcinoma treated with chemotherapy.

Xiaohong HanYing HanQiaoyun TanYu HuangJianliang YangSheng YangXiaohui HeShengyu ZhouYan SongJinping PiLijie ZuoJiarui YaoDi WuZhishang ZhangYuan-Kai Shi

Published in: Journal of translational medicine (2019)

Collectively, this work described the dynamic changes of ctDNA mutation status during platinum-based treatment, which may contribute to advanced lung adenocarcinoma patients stratification and precision treatment.

Keyphrases

circulating tumor
cell free
circulating tumor cells
end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
squamous cell carcinoma
combination therapy
cross sectional
prognostic factors
rectal cancer
dna methylation
copy number
nucleic acid