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Gut microbiota intervention alleviates pulmonary inflammation in broilers exposed to fine particulate matter from broiler house.

Junze LiuYuan LiDan ShenXiaoqing LiKai WangKentaro NagaokaChunmei Li
Published in: Applied and environmental microbiology (2024)
Gut microbes can influence the development of lung inflammation, and fine particulate matter collected from broiler houses can lead to lung inflammation in broilers. In this study, we explored the effect of gut microbes modified by intestinal non-absorbable antibiotics on particulate matter-induced lung inflammation. The results showed that modification in the composition of gut microbiota could alleviate lung inflammation by attenuating the ability of dendritic cells to stimulate T-cell differentiation, which provides a new way to protect lung health in poultry farms.
Keyphrases
  • particulate matter
  • air pollution
  • oxidative stress
  • dendritic cells
  • heat stress
  • healthcare
  • randomized controlled trial
  • public health
  • immune response
  • pulmonary hypertension
  • risk assessment
  • health information