Combination therapy of vitamin C and thiamine for septic shock: a multi-centre, double-blinded randomized, controlled study.

Sung Yeon HwangSeung Mok RyooJong Eun ParkYou Hwan JoDong-Hyun JangGil Joon SuhTaegyun KimYoun-Jung KimSeonwoo KimHyun ChoIk Joon JoSung Phil ChungSung-Hyuk ChoiTae-Gun ShinWon Young Kimnull null

Published in: Intensive care medicine (2020)

In this study, vitamin C and thiamine administration in the early phase of septic shock did not improve organ function compared with placebo, despite improvements in vitamin C and thiamine levels.

Keyphrases

septic shock
combination therapy
double blind
phase iii
placebo controlled
open label
clinical trial
randomized controlled trial