Login / Signup

MATE1 expression in the cochlea and its potential involvement in cisplatin cellular uptake and ototoxicity.

Sofia WaissbluthAgustín D MartínezCindel Figueroa-CaresHelmuth A SánchezJuan C Maass
Published in: Acta oto-laryngologica (2023)
To the best of our knowledge, this is the first study demonstrating the presence and localization of MATE1 in the cochlea. OCT2 labeling was seen in pillar cells. Consistently, OHCs and pillar cells uptake Texas Red cisplatin.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • healthcare
  • poor prognosis
  • endoplasmic reticulum stress
  • cell death
  • optical coherence tomography
  • pi k akt