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Comprehensive Inherited Risk Estimation for Risk-Based Breast Cancer Screening in Women.

Nina J MarsSini KerminenMax TamlanderMatti PirinenEveliina JakkulaKirsimari AaltonenTuomo MeretojaSirpa HeinävaaraElisabeth WidenSamuli Ripattinull null
Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Using real-life screening data, this study demonstrates the effectiveness of a breast cancer PRS for risk stratification, alone and combined with FH and PVs. Further research is required to evaluate their impact in a prospective risk-stratified screening program, including cost-effectiveness.
Keyphrases
  • randomized controlled trial
  • systematic review
  • breast cancer risk
  • metabolic syndrome
  • young adults
  • skeletal muscle
  • quality improvement
  • insulin resistance
  • data analysis
  • deep learning