Can magnetic resonance imaging enhance the assessment of potential new treatments for cognitive impairment in mood disorders? A systematic review and position paper by the International Society for Bipolar Disorders Targeting Cognition Task Force.
Kamilla Woznica MiskowiakNefize YalinIda SeebergKatherine E BurdickVicent Balanzá-MartínezCaterina Del Mar BonninChristopher R BowieAndre Fèrrer CarvalhoAnnemieke DolsKatie M DouglasPeter GallagherGregor HaslerLars Vedel KessingBeny LaferKathryn E LewandowskiCarlos López-JaramilloAnabel Martinez-AranRoger S McIntyreRichard A BryantScot E PurdonAyal SchafferTomiki SumiyoshiIvan J TorresTamsyn E Van RheenenLakshmi N YathamAllan H YoungEduard VietaPaul R A StokesPublished in: Bipolar disorders (2022)
Modulation of CCN and DMN activity is a putative efficacy biomarker. Methodological recommendations are to pre-declare intended analyses and use task-based fMRI, paradigms probing the CCN, longitudinal assessments, mock scanning, and out-of-scanner tests.
Keyphrases
- cognitive impairment
- magnetic resonance imaging
- bipolar disorder
- functional connectivity
- resting state
- computed tomography
- high resolution
- mild cognitive impairment
- cross sectional
- cancer therapy
- clinical practice
- single molecule
- molecular dynamics simulations
- white matter
- risk assessment
- multiple sclerosis
- drug delivery
- human health
- magnetic resonance
- physical activity
- climate change
- depressive symptoms