Characterization of antifungal C-type lectin receptor expression on murine epithelial and endothelial cells in mucosal tissues.

Mark H T StappersChristina NikolakopoulouDarin L WiesnerRaif YuecelBruce S KleinJanet A WillmentGordon D Brown

Published in: European journal of immunology (2021)

Our data reveal that selection of enzymes for generating single cell suspensions from murine tissues influences detection of surface expression of antifungal CLRs. Using a method that most preserves receptor expression, we show that non-myeloid expression of antifungal CLRs is limited to MelLec on endothelial cells in murine mucosal tissues.

Keyphrases

endothelial cells
candida albicans
single cell
poor prognosis
high glucose
rna seq
binding protein
bone marrow
ulcerative colitis
acute myeloid leukemia
electronic health record
long non coding rna
high throughput
label free