Expression of immune checkpoints on circulating tumor cells in men with metastatic prostate cancer.

Tian ZhangAnika AgarwalR Garland AlmquistDaniella RunyamboSally ParkElizabeth BronsonRengasamy BoominathanChandra RaoMonika AnandTaofik OyekunlePatrick HealyMegan A McNamaraKathryn WareJason A SomarelliDaniel J GeorgeAndrew J Armstrong

Published in: Biomarker research (2021)

We have identified that CTCs from men with mPC heterogeneously express immune checkpoints B7-H3, PD-L1, PD-L2, and CTLA-4, and the detection of these immune checkpoints may enable monitoring on immunotherapy.

Keyphrases

circulating tumor cells
prostate cancer
poor prognosis
squamous cell carcinoma
circulating tumor
middle aged
radical prostatectomy
label free
quantum dots