Nasal upregulation of CST1 in dog-sensitised children with severe allergic airway disease.

Ulrika KäckElisabet EinarsdottirMarianne van HageAnna AsarnojAnna JamesAnna NoppKaarel KrjutškovShintaro KatayamaJuha KereGunnar LiljaCilla SöderhällJon R Konradsen

Published in: ERJ open research (2021)

Overexpression of CST1 is associated with more severe allergic airway disease in children sensitised to dog dander. CST1 is thus a possible biomarker of the severity of allergic airway disease and a possible therapeutic target for the future treatment of airborne allergy.

Keyphrases

young adults
cell proliferation
early onset
particulate matter
signaling pathway
poor prognosis
drug induced
air pollution
infectious diseases
chronic rhinosinusitis