CKAP4, a DKK1 Receptor, Is a Biomarker in Exosomes Derived from Pancreatic Cancer and a Molecular Target for Therapy.

Hirokazu KimuraHideki YamamotoTakeshi HaradaKatsumi FumotoYoshihito OsugiRyota SadaNatsumi MaeharaHayato HikitaSoichiro MoriHidetoshi EguchiMasahito IkawaTetsuo TakeharaAkira Kikuchi

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

CKAP4 secreted in exosomes may represent a biomarker for PDAC. Anti-CKAP4 mAbs can contribute to the development of novel diagnostic methods and therapeutics.

Keyphrases

mesenchymal stem cells
stem cells
small molecule
single molecule
binding protein
replacement therapy
chemotherapy induced