Masahito Ikawa (M Ikawa, Masato Ikawa)

ResearcherID Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 165

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

Andrology

Communications biology

Osaka University

Osaka University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Osaka University

Japan

Distinguished Professor :: Research Institute for Micobial Diseases

Osaka University

Japan

Professor :: Research Institute for Microbial Diseases

Osaka University

Japan

Associate Professor :: Research Institute for Micobial Diseases

Osaka University

Japan

Assistant Professor :: Research Institute for Microbial Diseases

Osaka University

Japan

JSPS Research Fellow :: Research Institute for Micobial Diseases

Education History

Osaka University

Japan

PHD :: Pharmaceutical Sciences

Osaka University

Japan

MSC :: Pharmaceutical Sciences

Osaka University

Japan

BSC :: Pharmaceutical Sciences

Publications

Haoting Wang, Rie Iida-Norita, Daisuke Mashiko, Anh Hoang Pham, Haruhiko Miyata, Masahito Ikawa
Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads. PLoS genetics 20 (6) (2024)
Takafumi Kawai, Shin Morioka, Haruhiko Miyata, Rizki Tsari Andriani, Sharmin Akter, Gabriel Toma, Tatsuya Nakagawa, Yuki Oyama, Rie Iida-Norita, Junko Sasaki, Masahiko Watanabe, Kenji Sakimura, Masahito Ikawa, Takehiko Sasaki, Yasushi Okamura
The significance of electrical signals in maturing spermatozoa for phosphoinositide regulation through voltage-sensing phosphatase. Nature communications 15 (1) (2024)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. eLife 12 (2024)
Takahiro Akamine, Takeshi Terabayashi, Takako Sasaki, Riku Hayashi, Ichitaro Abe, Fumihiro Hirayama, Shin-Ichi Nureki, Masahito Ikawa, Haruhiko Miyata, Akinori Tokunaga, Takashi Kobayashi, Katsuhiro Hanada, Dean Thumkeo, Shuh Narumiya, Toshimasa Ishizaki
Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice. FEBS open bio 14 (6) (2024)
Hozaifa Metwally, Maha M Elbrashy, Tatsuhiko Ozawa, Kazuki Okuyama, Jason T White, Janyerkye Tulyeu, Jonas Nørskov Søndergaard, James Badger Wing, Arisa Muratsu, Hisatake Matsumoto, Masahito Ikawa, Hiroyuki Kishi, Ichiro Taniuchi, Tadamitsu Kishimoto
Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. eLife 12 (2024)
Takafumi Kawai, Shin Morioka, Haruhiko Miyata, Rizki Tsari Andriani, Sharmin Akter, Gabriel Toma, Tatsuya Nakagawa, Yuki Oyama, Rie Iida-Norita, Junko Sasaki, Masahiko Watanabe, Kenji Sakimura, Masahito Ikawa, Takehiko Sasaki, Yasushi Okamura
The significance of electrical signals in maturing spermatozoa for phosphoinositide regulation through voltage-sensing phosphatase. Nature communications 15 (1) (2024)
Tsutomu Endo, Kiyonori Kobayashi, Takafumi Matsumura, Chihiro Emori, Manabu Ozawa, Shimpei Kawamoto, Daisuke Okuzaki, Keisuke Shimada, Haruhiko Miyata, Kentaro Shimada, Mayo Kodani, Yu Ishikawa-Yamauchi, Daisuke Motooka, Eiji Hara, Masahito Ikawa
Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice. Communications biology 7 (1) (2024)
Yoshitaka Fujihara, Haruhiko Miyata, Ferheen Abbasi, Tamara Larasati, Kaori Nozawa, Zhifeng Yu, Masahito Ikawa, Martin M Matzuk
Tex46 knockout male mice are sterile secondary to sperm head malformations and failure to penetrate through the zona pellucida. PNAS nexus 3 (3) (2024)
Haruhiko Miyata, Keisuke Shimada, Yuki Kaneda, Masahito Ikawa
Development of functional spermatozoa in mammalian spermiogenesis. Development (Cambridge, England) 151 (14) (2024)
Tsutomu Endo, Kiyonori Kobayashi, Takafumi Matsumura, Chihiro Emori, Manabu Ozawa, Shimpei Kawamoto, Daisuke Okuzaki, Keisuke Shimada, Haruhiko Miyata, Kentaro Shimada, Mayo Kodani, Yu Ishikawa-Yamauchi, Daisuke Motooka, Eiji Hara, Masahito Ikawa
Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice. Communications biology 7 (1) (2024)
Yuki Kaneda, Haruhiko Miyata, Zoulan Xu, Keisuke Shimada, Maki Kamoshita, Tatsuya Nakagawa, Chihiro Emori, Masahito Ikawa
FBXO24 deletion causes abnormal accumulation of membraneless electron-dense granules in sperm flagella and male infertility. eLife 13 (2024)
Anh Hoang Pham, Chihiro Emori, Yu Ishikawa-Yamauchi, Keizo Tokuhiro, Maki Kamoshita, Yoshitaka Fujihara, Masahito Ikawa
Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice. Cells 13 (10) (2024)
Haoting Wang, Hiroko Kobayashi, Keisuke Shimada, Seiya Oura, Yuki Oyama, Hiroaki Kitakaze, Taichi Noda, Norikazu Yabuta, Haruhiko Miyata, Masahito Ikawa
MYCBPAP is a central apparatus protein required for centrosome-nuclear envelope docking and sperm tail biogenesis in mice. Journal of cell science 137 (16) (2024)
Tsutomu Endo, Kiyonori Kobayashi, Takafumi Matsumura, Chihiro Emori, Manabu Ozawa, Shimpei Kawamoto, Daisuke Okuzaki, Keisuke Shimada, Haruhiko Miyata, Kentaro Shimada, Mayo Kodani, Yu Ishikawa-Yamauchi, Daisuke Motooka, Eiji Hara, Masahito Ikawa
Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice. Communications biology 7 (1) (2024)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. bioRxiv : the preprint server for biology (2024)
Tsutomu Endo, Kiyonori Kobayashi, Takafumi Matsumura, Chihiro Emori, Manabu Ozawa, Shimpei Kawamoto, Daisuke Okuzaki, Keisuke Shimada, Haruhiko Miyata, Kentaro Shimada, Mayo Kodani, Yu Ishikawa-Yamauchi, Daisuke Motooka, Eiji Hara, Masahito Ikawa
Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice. Communications biology 7 (1) (2024)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. bioRxiv : the preprint server for biology (2024)
Yoshitaka Fujihara, Haruhiko Miyata, Ferheen Abbasi, Tamara Larasati, Kaori Nozawa, Zhifeng Yu, Masahito Ikawa, Martin M Matzuk
Tex46 knockout male mice are sterile secondary to sperm head malformations and failure to penetrate through the zona pellucida. PNAS nexus 3 (3) (2024)
Anh Hoang Pham, Chihiro Emori, Yu Ishikawa-Yamauchi, Keizo Tokuhiro, Maki Kamoshita, Yoshitaka Fujihara, Masahito Ikawa
Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice. Cells 13 (10) (2024)
Tsutomu Endo, Kiyonori Kobayashi, Takafumi Matsumura, Chihiro Emori, Manabu Ozawa, Shimpei Kawamoto, Daisuke Okuzaki, Keisuke Shimada, Haruhiko Miyata, Kentaro Shimada, Mayo Kodani, Yu Ishikawa-Yamauchi, Daisuke Motooka, Eiji Hara, Masahito Ikawa
Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice. Communications biology 7 (1) (2024)
Haoting Wang, Hiroko Kobayashi, Keisuke Shimada, Seiya Oura, Yuki Oyama, Hiroaki Kitakaze, Taichi Noda, Norikazu Yabuta, Haruhiko Miyata, Masahito Ikawa
MYCBPAP is a central apparatus protein required for centrosome-nuclear envelope docking and sperm tail biogenesis in mice. Journal of cell science (2024)
Haoting Wang, Rie Iida-Norita, Daisuke Mashiko, Anh Hoang Pham, Haruhiko Miyata, Masahito Ikawa
Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads. PLoS genetics 20 (6) (2024)
Jiyeon Lee, Fumiyuki Sasaki, Eri Koike, Minjeong Cho, Yeongun Lee, So Hee Dho, Jina Lee, Eunji Lee, Eri Toyohara, Mika Sunakawa, Mariko Ishibashi, Huynh Hiep Hung, Saki Nishioka, Ritsuko Komine, Chiaki Okura, Masumi Shimizu, Masahito Ikawa, Akihiko Yoshimura, Rimpei Morita, Lark Kyun Kim
Gelsolin alleviates rheumatoid arthritis by negatively regulating NLRP3 inflammasome activation. Cell death and differentiation (2024)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. eLife 12 (2024)
Takahiro Akamine, Takeshi Terabayashi, Takako Sasaki, Riku Hayashi, Ichitaro Abe, Fumihiro Hirayama, Shin-Ichi Nureki, Masahito Ikawa, Haruhiko Miyata, Akinori Tokunaga, Takashi Kobayashi, Katsuhiro Hanada, Dean Thumkeo, Shuh Narumiya, Toshimasa Ishizaki
Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice. FEBS open bio 14 (6) (2024)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. bioRxiv : the preprint server for biology (2024)
Takahiro Akamine, Takeshi Terabayashi, Takako Sasaki, Riku Hayashi, Ichitaro Abe, Fumihiro Hirayama, Shin-Ichi Nureki, Masahito Ikawa, Haruhiko Miyata, Akinori Tokunaga, Takashi Kobayashi, Katsuhiro Hanada, Dean Thumkeo, Shuh Narumiya, Toshimasa Ishizaki
Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice. FEBS open bio (2024)
Yuki Kaneda, Haruhiko Miyata, Zoulan Xu, Keisuke Shimada, Maki Kamoshita, Tatsuya Nakagawa, Chihiro Emori, Masahito Ikawa
FBXO24 deletion causes abnormal accumulation of membraneless electron-dense granules in sperm flagella and male infertility. eLife 13 (2024)
Hozaifa Metwally, Maha M Elbrashy, Tatsuhiko Ozawa, Kazuki Okuyama, Jason T White, Janyerkye Tulyeu, Jonas Nørskov Søndergaard, James Badger Wing, Arisa Muratsu, Hisatake Matsumoto, Masahito Ikawa, Hiroyuki Kishi, Ichiro Taniuchi, Tadamitsu Kishimoto
Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Takahiro Akamine, Takeshi Terabayashi, Takako Sasaki, Riku Hayashi, Ichitaro Abe, Fumihiro Hirayama, Shin-Ichi Nureki, Masahito Ikawa, Haruhiko Miyata, Akinori Tokunaga, Takashi Kobayashi, Katsuhiro Hanada, Dean Thumkeo, Shuh Narumiya, Toshimasa Ishizaki
Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice. FEBS open bio 14 (6) (2024)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. eLife 12 (2024)
Hozaifa Metwally, Maha M Elbrashy, Tatsuhiko Ozawa, Kazuki Okuyama, Jason T White, Janyerkye Tulyeu, Jonas Nørskov Søndergaard, James Badger Wing, Arisa Muratsu, Hisatake Matsumoto, Masahito Ikawa, Hiroyuki Kishi, Ichiro Taniuchi, Tadamitsu Kishimoto
Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Hozaifa Metwally, Maha M Elbrashy, Tatsuhiko Ozawa, Kazuki Okuyama, Jason T White, Janyerkye Tulyeu, Jonas Nørskov Søndergaard, James Badger Wing, Arisa Muratsu, Hisatake Matsumoto, Masahito Ikawa, Hiroyuki Kishi, Ichiro Taniuchi, Tadamitsu Kishimoto
Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Yoshitaka Fujihara, Haruhiko Miyata, Ferheen Abbasi, Tamara Larasati, Kaori Nozawa, Zhifeng Yu, Masahito Ikawa, Martin M Matzuk
Tex46 knockout male mice are sterile secondary to sperm head malformations and failure to penetrate through the zona pellucida. PNAS nexus 3 (3) (2024)
Haoting Wang, Rie Iida-Norita, Daisuke Mashiko, Anh Hoang Pham, Haruhiko Miyata, Masahito Ikawa
Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads. PLoS genetics 20 (6) (2024)
Haoting Wang, Rie Iida-Norita, Daisuke Mashiko, Anh Hoang Pham, Haruhiko Miyata, Masahito Ikawa
Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads. PLoS genetics 20 (6) (2024)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. eLife 12 (2024)
Haoting Wang, Hiroko Kobayashi, Keisuke Shimada, Seiya Oura, Yuki Oyama, Hiroaki Kitakaze, Taichi Noda, Norikazu Yabuta, Haruhiko Miyata, Masahito Ikawa
MYCBPAP is a central apparatus protein required for centrosome-nuclear envelope docking and sperm tail biogenesis in mice. Journal of cell science 137 (16) (2024)
Yoshitaka Fujihara, Haruhiko Miyata, Ferheen Abbasi, Tamara Larasati, Kaori Nozawa, Zhifeng Yu, Masahito Ikawa, Martin M Matzuk
Tex46 knockout male mice are sterile secondary to sperm head malformations and failure to penetrate through the zona pellucida. PNAS nexus 3 (3) (2024)
Yuki Kaneda, Haruhiko Miyata, Zoulan Xu, Keisuke Shimada, Maki Kamoshita, Tatsuya Nakagawa, Chihiro Emori, Masahito Ikawa
FBXO24 deletion causes abnormal accumulation of membraneless electron-dense granules in sperm flagella and male infertility. eLife 13 (2024)
Haoting Wang, Rie Iida-Norita, Daisuke Mashiko, Anh Hoang Pham, Haruhiko Miyata, Masahito Ikawa
Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads. PLoS genetics 20 (6) (2024)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. bioRxiv : the preprint server for biology (2024)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. bioRxiv : the preprint server for biology (2024)
Akane Morohoshi, Haruhiko Miyata, Keizo Tokuhiro, Rie Iida-Norita, Taichi Noda, Yoshitaka Fujihara, Masahito Ikawa
Testis-enriched ferlin, FER1L5, is required for Ca 2+ -activated acrosome reaction and male fertility. Science advances 9 (4) (2023)
Daiji Kiyozumi, Kentaro Shimada, Michael Chalick, Chihiro Emori, Mayo Kodani, Seiya Oura, Taichi Noda, Tsutomu Endo, Martin M Matzuk, Daniel H Wreschner, Masahito Ikawa
A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility. Nature communications 14 (1) (2023)
Yuki Kaneda, Haruhiko Miyata, Zoulan Xu, Keisuke Shimada, Maki Kamoshita, Tatsuya Nakagawa, Chihiro Emori, Masahito Ikawa
FBXO24 ensures male fertility by preventing abnormal accumulation of membraneless granules in sperm flagella. bioRxiv : the preprint server for biology (2023)
Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Mayumi Kinoshita, Rina Hashimoto, Naoya Shigesada, Junya Takahashi, Masashi Tachibana, Shota Tanaka, Masanori Obana, Nobumasa Hino, Masahito Ikawa, Kazutake Tsujikawa, Chikako Ono, Yoshiharu Matsuura, Hiroyasu Kidoya, Nobuyuki Takakura, Yoshiaki Kubota, Takefumi Doi, Kazuo Takayama, Yasuo Yoshioka, Yasushi Fujio, Yoshiaki Okada
Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Yonggang Lu, Kentaro Shimada, Shaogeng Tang, Jingjing Zhang, Yo Ogawa, Taichi Noda, Hiroki Shibuya, Masahito Ikawa
1700029I15Rik orchestrates the biosynthesis of acrosomal membrane proteins required for sperm-egg interaction. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Keisuke Shimada, Soojin Park, Seiya Oura, Taichi Noda, Akane Morohoshi, Martin M Matzuk, Masahito Ikawa
TSKS localizes to nuage in spermatids and regulates cytoplasmic elimination during spermiation. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Keisuke Shimada, Soojin Park, Seiya Oura, Taichi Noda, Akane Morohoshi, Martin M Matzuk, Masahito Ikawa
TSKS localizes to nuage in spermatids and regulates cytoplasmic elimination during spermiation. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Yuki Kaneda, Haruhiko Miyata, Keisuke Shimada, Seiya Oura, Masahito Ikawa
Testis-specific proteins, TSNAXIP1 and 1700010I14RIK, are important for sperm motility and male fertility in mice. Andrology (2023)
Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Mayumi Kinoshita, Rina Hashimoto, Naoya Shigesada, Junya Takahashi, Masashi Tachibana, Shota Tanaka, Masanori Obana, Nobumasa Hino, Masahito Ikawa, Kazutake Tsujikawa, Chikako Ono, Yoshiharu Matsuura, Hiroyasu Kidoya, Nobuyuki Takakura, Yoshiaki Kubota, Takefumi Doi, Kazuo Takayama, Yasuo Yoshioka, Yasushi Fujio, Yoshiaki Okada
Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Pierre Ferrer, S Upadhyay, Masahito Ikawa, Tracy M Clement
Testis-specific actin-like 7A (ACTL7A) is an indispensable protein for subacrosomal-associated F-actin formation, acrosomal anchoring, and male fertility. Molecular human reproduction 29 (3) (2023)
Xiaofang Huang, Haruhiko Miyata, Huafeng Wang, Giulia Mori, Rie Iida-Norita, Masahito Ikawa, Riccardo Percudani, Jean-Ju Chung
A CUG-initiated CATSPERθ functions in the CatSper channel assembly and serves as a checkpoint for flagellar trafficking. bioRxiv : the preprint server for biology (2023)
Daiji Kiyozumi, Kentaro Shimada, Michael Chalick, Chihiro Emori, Mayo Kodani, Seiya Oura, Taichi Noda, Tsutomu Endo, Martin M Matzuk, Daniel H Wreschner, Masahito Ikawa
A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility. Nature communications 14 (1) (2023)
Taiichiro Shirai, Akiko Nakai, Emiko Ando, Jun Fujimoto, Sarah Leach, Takao Arimori, Daisuke Higo, Floris J van Eerden, Janyerkye Tulyeu, Yu-Chen Liu, Daisuke Okuzaki, Masanori A Murayama, Haruhiko Miyata, Kazuto Nunomura, Bangzhong Lin, Akiyoshi Tani, Atsushi Kumanogoh, Masahito Ikawa, James Badger Wing, Daron M Standley, Junichi Takagi, Kazuhiro Suzuki
Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex. Science immunology 8 (81) (2023)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. bioRxiv : the preprint server for biology (2023)
Sohei Kuribayashi, Shinichiro Fukuhara, Go Tsujimura, Takahiro Imanaka, Koichi Okada, Norichika Ueda, Kentaro Takezawa, Hiroshi Kiuchi, Shigeyoshi Saito, Yusuke Takahashi, Hidetaka Kioka, Seiya Oura, Keisuke Shimada, Masahito Ikawa, Norio Nonomura
Evaluation of the efficacy of creatine chemical exchange saturation transfer imaging in assessing testicular maturity. Reproductive medicine and biology 22 (1) (2023)
Courtney M Sutton, Kaori Nozawa, Katarzyna Kent, Alexander B Saltzman, Mei Leng, Sureshbabu Nagarajan, Anna Malovannaya, Masahito Ikawa, Thomas X Garcia, Martin M Matzuk
Molecular dissection and testing of PRSS37 function through LC-MS/MS and the generation of a PRSS37 humanized mouse model. Scientific reports 13 (1) (2023)
Yonggang Lu, Ippei Nagamori, Hisato Kobayashi, Kanako Kojima-Kita, Kenjiro Shirane, Hsin-Yi Chang, Toru Nishimura, Takayuki Koyano, Zhifeng Yu, Julio M Castañeda, Makoto Matsuyama, Satomi Kuramochi-Miyagawa, Martin M Matzuk, Masahito Ikawa
ADAD2 functions in spermiogenesis and piRNA biogenesis in mice. Andrology (2023)
Yonggang Lu, Kentaro Shimada, Shaogeng Tang, Jingjing Zhang, Yo Ogawa, Taichi Noda, Hiroki Shibuya, Masahito Ikawa
1700029I15Rik orchestrates the biosynthesis of acrosomal membrane proteins required for sperm-egg interaction. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Yuki Kaneda, Haruhiko Miyata, Keisuke Shimada, Seiya Oura, Masahito Ikawa
Testis-specific proteins, TSNAXIP1 and 1700010I14RIK, are important for sperm motility and male fertility in mice. Andrology (2023)
Taiichiro Shirai, Akiko Nakai, Emiko Ando, Jun Fujimoto, Sarah Leach, Takao Arimori, Daisuke Higo, Floris J van Eerden, Janyerkye Tulyeu, Yu-Chen Liu, Daisuke Okuzaki, Masanori A Murayama, Haruhiko Miyata, Kazuto Nunomura, Bangzhong Lin, Akiyoshi Tani, Atsushi Kumanogoh, Masahito Ikawa, James Badger Wing, Daron M Standley, Junichi Takagi, Kazuhiro Suzuki
Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex. Science immunology 8 (81) (2023)
Yonggang Lu, Kentaro Shimada, Shaogeng Tang, Jingjing Zhang, Yo Ogawa, Taichi Noda, Hiroki Shibuya, Masahito Ikawa
1700029I15Rik orchestrates the biosynthesis of acrosomal membrane proteins required for sperm-egg interaction. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Keisuke Shimada, Masahito Ikawa
CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility. Development (Cambridge, England) (2023)
Yonggang Lu, Ippei Nagamori, Hisato Kobayashi, Kanako Kojima-Kita, Kenjiro Shirane, Hsin-Yi Chang, Toru Nishimura, Takayuki Koyano, Zhifeng Yu, Julio M Castañeda, Makoto Matsuyama, Satomi Kuramochi-Miyagawa, Martin M Matzuk, Masahito Ikawa
ADAD2 functions in spermiogenesis and piRNA biogenesis in mice. Andrology (2023)
Zian Liao, Suni Tang, Kaori Nozawa, Keisuke Shimada, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy. bioRxiv : the preprint server for biology (2023)
Yonggang Lu, Ippei Nagamori, Hisato Kobayashi, Kanako Kojima-Kita, Kenjiro Shirane, Hsin-Yi Chang, Toru Nishimura, Takayuki Koyano, Zhifeng Yu, Julio M Castañeda, Makoto Matsuyama, Satomi Kuramochi-Miyagawa, Martin M Matzuk, Masahito Ikawa
ADAD2 functions in spermiogenesis and piRNA biogenesis in mice. Andrology (2023)
Akane Morohoshi, Haruhiko Miyata, Keizo Tokuhiro, Rie Iida-Norita, Taichi Noda, Yoshitaka Fujihara, Masahito Ikawa
Testis-enriched ferlin, FER1L5, is required for Ca 2+ -activated acrosome reaction and male fertility. Science advances 9 (4) (2023)
Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Mayumi Kinoshita, Rina Hashimoto, Naoya Shigesada, Junya Takahashi, Masashi Tachibana, Shota Tanaka, Masanori Obana, Nobumasa Hino, Masahito Ikawa, Kazutake Tsujikawa, Chikako Ono, Yoshiharu Matsuura, Hiroyasu Kidoya, Nobuyuki Takakura, Yoshiaki Kubota, Takefumi Doi, Kazuo Takayama, Yasuo Yoshioka, Yasushi Fujio, Yoshiaki Okada
Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Akane Morohoshi, Haruhiko Miyata, Keizo Tokuhiro, Rie Iida-Norita, Taichi Noda, Yoshitaka Fujihara, Masahito Ikawa
Testis-enriched ferlin, FER1L5, is required for Ca 2+ -activated acrosome reaction and male fertility. Science advances 9 (4) (2023)
Keisuke Shimada, Soojin Park, Seiya Oura, Taichi Noda, Akane Morohoshi, Martin M Matzuk, Masahito Ikawa
TSKS localizes to nuage in spermatids and regulates cytoplasmic elimination during spermiation. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Koei Shinzawa, Shinji Matsumoto, Ryota Sada, Akikazu Harada, Kaori Saitoh, Keiko Kato, Satsuki Ikeda, Akiyoshi Hirayama, Kazunori Yokoi, Atsushi Tanemura, Keisuke Nimura, Masahito Ikawa, Tomoyoshi Soga, Akira Kikuchi
GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation. Oncogene (2023)
Yonggang Lu, Kentaro Shimada, Shaogeng Tang, Jingjing Zhang, Yo Ogawa, Taichi Noda, Hiroki Shibuya, Masahito Ikawa
1700029I15Rik orchestrates the biosynthesis of acrosomal membrane proteins required for sperm-egg interaction. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Akane Morohoshi, Haruhiko Miyata, Keizo Tokuhiro, Rie Iida-Norita, Taichi Noda, Yoshitaka Fujihara, Masahito Ikawa
Testis-enriched ferlin, FER1L5, is required for Ca 2+ -activated acrosome reaction and male fertility. Science advances 9 (4) (2023)
Katarzyna Kent, Kaori Nozawa, Courtney M Sutton, Frey Daniel, Masahito Ikawa, Thomas X Garcia, Martin M Matzuk
CUB domains are not required for OVCH2 function in sperm maturation in the mouse epididymis. Andrology (2023)
Yuki Kaneda, Haruhiko Miyata, Keisuke Shimada, Seiya Oura, Masahito Ikawa
Testis-specific proteins, TSNAXIP1 and 1700010I14RIK, are important for sperm motility and male fertility in mice. Andrology (2023)
Yo Ogawa, Yonggang Lu, Daiji Kiyozumi, Hsin-Yi Chang, Masahito Ikawa
CRISPR/Cas9-mediated genome editing reveals seven testis-enriched transmembrane glycoproteins dispensable for male fertility in mice. Andrology (2023)
Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Mayumi Kinoshita, Rina Hashimoto, Naoya Shigesada, Junya Takahashi, Masashi Tachibana, Shota Tanaka, Masanori Obana, Nobumasa Hino, Masahito Ikawa, Kazutake Tsujikawa, Chikako Ono, Yoshiharu Matsuura, Hiroyasu Kidoya, Nobuyuki Takakura, Yoshiaki Kubota, Takefumi Doi, Kazuo Takayama, Yasuo Yoshioka, Yasushi Fujio, Yoshiaki Okada
Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Keisuke Shimada, Soojin Park, Seiya Oura, Taichi Noda, Akane Morohoshi, Martin M Matzuk, Masahito Ikawa
TSKS localizes to nuage in spermatids and regulates cytoplasmic elimination during spermiation. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Daiji Kiyozumi, Kentaro Shimada, Michael Chalick, Chihiro Emori, Mayo Kodani, Seiya Oura, Taichi Noda, Tsutomu Endo, Martin M Matzuk, Daniel H Wreschner, Masahito Ikawa
A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility. Nature communications 14 (1) (2023)
Yonggang Lu, Kentaro Shimada, Shaogeng Tang, Jingjing Zhang, Yo Ogawa, Taichi Noda, Hiroki Shibuya, Masahito Ikawa
1700029I15Rik orchestrates the biosynthesis of acrosomal membrane proteins required for sperm-egg interaction. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Xiaofang Huang, Haruhiko Miyata, Huafeng Wang, Giulia Mori, Rie Iida-Norita, Masahito Ikawa, Riccardo Percudani, Jean-Ju Chung
A CUG-initiated CATSPERθ functions in the CatSper channel assembly and serves as a checkpoint for flagellar trafficking. Proceedings of the National Academy of Sciences of the United States of America 120 (39) (2023)
Pierre Ferrer, S Upadhyay, Masahito Ikawa, Tracy M Clement
Testis-specific actin-like 7A (ACTL7A) is an indispensable protein for subacrosomal-associated F-actin formation, acrosomal anchoring, and male fertility. Molecular human reproduction 29 (3) (2023)
Kaori Nozawa, Zian Liao, Yuhkoh Satouh, Ting Geng, Masahito Ikawa, Diana Monsivais, Martin M Matzuk
Oocyte-specific Wee1-like protein kinase 2 is dispensable for fertility in mice. PloS one 18 (8) (2023)
Keisuke Shimada, Soojin Park, Seiya Oura, Taichi Noda, Akane Morohoshi, Martin M Matzuk, Masahito Ikawa
TSKS localizes to nuage in spermatids and regulates cytoplasmic elimination during spermiation. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Sohei Kuribayashi, Shinichiro Fukuhara, Go Tsujimura, Takahiro Imanaka, Koichi Okada, Norichika Ueda, Kentaro Takezawa, Hiroshi Kiuchi, Shigeyoshi Saito, Yusuke Takahashi, Hidetaka Kioka, Seiya Oura, Keisuke Shimada, Masahito Ikawa, Norio Nonomura
Evaluation of the efficacy of creatine chemical exchange saturation transfer imaging in assessing testicular maturity. Reproductive medicine and biology 22 (1) (2023)
Daiji Kiyozumi, Kentaro Shimada, Michael Chalick, Chihiro Emori, Mayo Kodani, Seiya Oura, Taichi Noda, Tsutomu Endo, Martin M Matzuk, Daniel H Wreschner, Masahito Ikawa
A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility. Nature communications 14 (1) (2023)
Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Mayumi Kinoshita, Rina Hashimoto, Naoya Shigesada, Junya Takahashi, Masashi Tachibana, Shota Tanaka, Masanori Obana, Nobumasa Hino, Masahito Ikawa, Kazutake Tsujikawa, Chikako Ono, Yoshiharu Matsuura, Hiroyasu Kidoya, Nobuyuki Takakura, Yoshiaki Kubota, Takefumi Doi, Kazuo Takayama, Yasuo Yoshioka, Yasushi Fujio, Yoshiaki Okada
Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Yonggang Lu, Kentaro Shimada, Shaogeng Tang, Jingjing Zhang, Yo Ogawa, Taichi Noda, Hiroki Shibuya, Masahito Ikawa
1700029I15Rik orchestrates the biosynthesis of acrosomal membrane proteins required for sperm-egg interaction. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Mayumi Kinoshita, Rina Hashimoto, Naoya Shigesada, Junya Takahashi, Masashi Tachibana, Shota Tanaka, Masanori Obana, Nobumasa Hino, Masahito Ikawa, Kazutake Tsujikawa, Chikako Ono, Yoshiharu Matsuura, Hiroyasu Kidoya, Nobuyuki Takakura, Yoshiaki Kubota, Takefumi Doi, Kazuo Takayama, Yasuo Yoshioka, Yasushi Fujio, Yoshiaki Okada
Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Yonggang Lu, Kentaro Shimada, Shaogeng Tang, Jingjing Zhang, Yo Ogawa, Taichi Noda, Hiroki Shibuya, Masahito Ikawa
1700029I15Rik orchestrates the biosynthesis of acrosomal membrane proteins required for sperm-egg interaction. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Yuki Kaneda, Haruhiko Miyata, Keisuke Shimada, Seiya Oura, Masahito Ikawa
Testis-specific proteins, TSNAXIP1 and 1700010I14RIK, are important for sperm motility and male fertility in mice. Andrology (2023)
Daiji Kiyozumi, Kentaro Shimada, Michael Chalick, Chihiro Emori, Mayo Kodani, Seiya Oura, Taichi Noda, Tsutomu Endo, Martin M Matzuk, Daniel H Wreschner, Masahito Ikawa
A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility. Nature communications 14 (1) (2023)
Akane Morohoshi, Haruhiko Miyata, Keizo Tokuhiro, Rie Iida-Norita, Taichi Noda, Yoshitaka Fujihara, Masahito Ikawa
Testis-enriched ferlin, FER1L5, is required for Ca 2+ -activated acrosome reaction and male fertility. Science advances 9 (4) (2023)
Yamato Fukui, Yasushi Hirota, Tomoko Saito-Fujita, Shizu Aikawa, Takehiro Hiraoka, Tetsuaki Kaku, Tomoyuki Hirata, Shun Akaeda, Mitsunori Matsuo, Ryoko Shimizu-Hirota, Norihiko Takeda, Masahito Ikawa, Yutaka Osuga
Uterine Epithelial LIF Receptors Contribute to Implantation Chamber Formation in Blastocyst Attachment. Endocrinology 162 (11) (2022)
Rina Hashimoto, Junya Takahashi, Keisuke Shirakura, Risa Funatsu, Kaori Kosugi, Sayaka Deguchi, Masaki Yamamoto, Yugo Tsunoda, Maaya Morita, Kosuke Muraoka, Masato Tanaka, Tomoaki Kanbara, Shota Tanaka, Shigeyuki Tamiya, Nagisa Tokunoh, Atsushi Kawai, Masahito Ikawa, Chikako Ono, Keisuke Tachibana, Masuo Kondoh, Masanori Obana, Yoshiharu Matsuura, Akihiro Ohsumi, Takeshi Noda, Takuya Yamamoto, Yasuo Yoshioka, Yu-Suke Torisawa, Hiroshi Date, Yasushi Fujio, Miki Nagao, Kazuo Takayama, Yoshiaki Okada
SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression. Science advances 8 (38) (2022)
Yoshitaka Fujihara, Kiyonori Kobayashi, Ferheen Abbasi, Tsutomu Endo, Zhifeng Yu, Masahito Ikawa, Martin M Matzuk
PDCL2 is essential for sperm acrosome formation and male fertility in mice. Andrology (2022)
Yuki Oyama, Haruhiko Miyata, Keisuke Shimada, Tamara Larasati, Yoshitaka Fujihara, Masahito Ikawa
TULP2 deletion mice exhibit abnormal outer dense fiber structure and male infertility. Reproductive medicine and biology 21 (1) (2022)

Masahito Ikawa.css-eqlu8i{font-size:small;padding-left:4px;} (M Ikawa, Masato Ikawa)

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Masahito Ikawa (M Ikawa, Masato Ikawa)