Germinal center TFH cells: T(w)o be or not t(w)o be, IL-6 is the answer.

Published in: Science immunology (2020)

IL-6 inhibits the expression of IL-2Rβ (CD122) in germinal center TFH cells to maintain IL-2 hyporesponsiveness (see the related Research Article by Papillion et al.).

Keyphrases

induced apoptosis
cell cycle arrest
poor prognosis
endoplasmic reticulum stress
cell death
long non coding rna