Abdominal Parietal Metastasis from Cervical Cancer: A Review of One of the Most Uncommon Sites of Recurrence Including a Report of a New Case.
Irinel-Gabriel Dicu-AndreescuMarian-Augustin MarincașAnca Angela SimionescuIoana Dicu-AndreescuVirgiliu Mihail PrunoiuSinziana-Octavia IonescuȘtefania-Ariana NeicuGabriela-Mădălina RaduEugen BrătucuLaurențiu SimionPublished in: Life (Basel, Switzerland) (2024)
Cervical cancer is the fourth most common cancer in women, the highest mortality being found in low- and middle-income countries. Abdominal parietal metastases in cervical cancer are a very rare entity, with an incidence of 0.1-1.3%, and represent an unfavorable prognostic factor with the survival rate falling to 17%. Here, we present a review of cases of abdominal parietal metastasis in recent decades, including a new case of a 4.5 cm abdominal parietal metastasis at the site of the scar of the former drain tube 28 months after diagnosis of stage IIB cervical cancer (adenosquamous carcinoma), treated by external radiotherapy with concurrent chemotherapy and intracavitary brachytherapy and subsequent surgery (type B radical hysterectomy). The tumor was resected within oncological limits with the histopathological result of adenosquamous carcinoma. The case study highlights the importance of early detection and appropriate treatment of metastases in patients with cervical cancer. The discussion explores the potential pathways for parietal metastasis and the impact of incomplete surgical procedures on the development of metastases. The conclusion emphasizes the poor prognosis associated with this type of metastasis in cervical cancer patients and the potential benefits of surgical resection associated with systemic therapy in improving survival rates.
Keyphrases
- poor prognosis
- working memory
- prognostic factors
- locally advanced
- long non coding rna
- risk factors
- rectal cancer
- high dose
- squamous cell carcinoma
- prostate cancer
- early stage
- stem cells
- type diabetes
- lymph node
- cardiovascular events
- coronary artery disease
- pregnant women
- bone marrow
- cardiovascular disease
- low dose
- skeletal muscle
- replacement therapy
- atrial fibrillation
- drug induced