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H3K9me3, H3K36me3, and H4K20me3 Expression Correlates with Patient Outcome in Esophageal Squamous Cell Carcinoma as Epigenetic Markers.

Menghan ZhouYiping LiShaofeng LinYanping ChenYanyan QianZhujiang ZhaoHong Fan
Published in: Digestive diseases and sciences (2019)
H3K9me3, H4K20me3, and H3K36me3 showed a close relationship with clinical features and were considered independent risk factors for survival of ESCC patients. The combination of H3K9me3, H4K20me3, and H3K36me3 expression, rather than the expression of a single histone marker, is believed to further enhance evaluations of ESCC prognosis and management.
Keyphrases
  • poor prognosis
  • end stage renal disease
  • dna methylation
  • newly diagnosed
  • ejection fraction
  • gene expression
  • binding protein
  • chronic kidney disease
  • long non coding rna
  • case report
  • peritoneal dialysis
  • free survival