3D genome alterations in T cells associated with disease activity of systemic lupus erythematosus.

Ming ZhaoDelong FengLongyuan HuLin LiuJiali WuZhi HuHaojun LongQiqi KuangLianlian OuyangQianjin Lu

Published in: Annals of the rheumatic diseases (2022)

Our results highlight the 3D genome structure alterations associated with SLE development and provide a foundation for future interrogation of the relationships between chromosome structure and gene expression control in SLE.

Keyphrases

systemic lupus erythematosus
disease activity
gene expression
rheumatoid arthritis patients
rheumatoid arthritis
ankylosing spondylitis
juvenile idiopathic arthritis
genome wide
dna methylation
copy number