ATG16L1 rs2241880/T300A increases susceptibility to perianal Crohn's disease: An updated meta-analysis on inflammatory bowel disease risk and clinical outcomes.

Isidora SimovicIda HilmiRuey Terng NgKee Seang ChewShin Yee WongWay Seah LeeStephen RiordanNatalia Castaño-Rodríguez

Published in: United European gastroenterology journal (2023)

ATG16L1 rs2241880 (G allele) is a consistent risk factor for IBD in Caucasian cohorts and influences clinical outcomes. As its role in non-Caucasian populations remains ambiguous, further studies in under-reported populations are necessary.

Keyphrases

systematic review
case control
african american
meta analyses
genetic diversity
randomized controlled trial
breast cancer risk