Expression of the type 3 InsP3 receptor is a final common event in the development of hepatocellular carcinoma.
Mateus T GuerraRodrigo M FlorentinoAndressa FrancaAntonio C Lima FilhoMarcone L Dos SantosRoberta C FonsecaFernanda O LemosMatheus C FonsecaEmma KruglovAlbert MennoneBasile NjeiJoanna GibsonFulan GuanYung-Chi ChengMeenakshisundaram AnanthanarayananJianlei GuJianping JiangHongyu ZhaoCristiano X LimaPaula T VidigalAndre G OliveiraMichael H NathansonMaria Fatima LeitePublished in: Gut (2019)
These results provide evidence that de novo expression of ITPR3 typically occurs in HCC and may play a role in its pathogenesis.