A pilot study of LINE-1 copy number and telomere length with aging in human sperm.
Thalita S BerteliFang WangPaula Andrea NavarroFabiana Barzotto KohlrauschDavid Lawrence KeefePublished in: Journal of assisted reproduction and genetics (2023)
Elongation of telomeres in the male germline could repress retrotransposition, which tends to increase with cellular aging. More studies in larger cohorts across a wide age span are needed to confirm our conclusions and explore their biological and clinical significance.