Histone deacetylase-mediated silencing of PSTPIP2 expression contributes to AAI-induced PANoptosis.
Chuanting XuQi WangChanglin DuJiahui DongZhenming ZhangNa CaiJun LiCheng HuangTaotao Ma
Published in: British journal of pharmacology (2023)
HDAC-mediated silencing of PSTPIP2 may contribute to aristolochic acid nephropathy. Hence, HDAC1 and -2 specific inhibitors or PSTPIP2 could be valuable therapeutic agents for preventing aristolochic acid nephropathy.