Calcium pantothenate is present in cosmetics and may cause allergic contact dermatitis.
Maria-Antonia Pastor-NietoMaria-Elena Gatica-OrtegaConsuelo Sánchez-HerrerosEsther Jiménez-BlázquezAdriana Martín-FuentesIván Checa-RecioPablo Cobo-RodríguezYuri Rodrigues-FigueiraJesús Cuevas-SantosEsther De-Eusebio-MurilloPublished in: Contact dermatitis (2020)
Calcium pantothenate (CAS no. 137-08-6) is the calcium salt of pantothenic acid (vitamin B5). It is used in cosmetics due to its anti-static and hair conditioning properties. A 53-year-old female nurse's aide presented with intermittent facial eruptions (Figure S1). Patch tests were positive to calcium pantothenate, an ingredient of two of her products (a cleansing milk and a facial tonic). To our knowledge, no previous cases of sensitization from calcium pantothenate have been reported except for one case of systemic dermatitis from a nutritional supplement in a dexpanthenol-sensitized patient.