Login / Signup

Correlation analysis of cancer stem cell marker CD133 and human endogenous retrovirus (HERV)-K env in SKOV3 ovarian cancer cells.

Do-Ye KimHeungyeol KimEun-Ji KoSuk Bong KohHongbae KimJi Young LeeChul Min LeeWan Kyu EoKi Hyung KimHee Jae Cha
Published in: Genes & genomics (2024)
These findings indicate that the expression of HERV-K env increased in SKOV3 cells when cultured in cancer stem cell induction media, and cancer stem cell induction was inhibited by KO of HERV-K env in SKOV3 cells. These results suggest a strong association between HERV-K env and stemness in SKOV3 ovarian cancer cells.
Keyphrases
  • cancer stem cells
  • induced apoptosis
  • endothelial cells
  • cell cycle arrest
  • poor prognosis
  • stem cells
  • endoplasmic reticulum stress
  • epithelial mesenchymal transition
  • induced pluripotent stem cells
  • nk cells