CD133 and epithelial cell adhesion molecule expressions in the cholangiocarcinoma component are prognostic factors for combined hepatocellular cholangiocarcinoma.
Kazuki WakizakaHideki YokooToshiya KamiyamaTatsuhiko KakisakaMasafumi OhiraMichio TaniKoichi KatoYuki FujiiKo SugiyamaAkihisa NagatsuShingo ShimadaTatsuya OrimoHirofumi KamachiRyosuke MatsuokaAkinobu TaketomiPublished in: Hepatology research : the official journal of the Japan Society of Hepatology (2019)
INT and CCA components showed higher expression rates of cancer stem cell markers than the HCC component. CD133 or EpCAM expression in the CCA component was associated with poor prognosis in cHCC-CCA.