Propofol protects against lipopolysaccharide-induced inflammatory response in human amnion-derived WISH cells.

Cheul-Hong Kim Sang-Hoon Lee Ji-Young Yoon Eun-Jung Kim Jong Hoon Joo Yeon Ha Kim Eun-Ji Choi

Published in: Journal of dental anesthesia and pain medicine (2022)

Propofol does not affect the viability of WISH cells and inhibits LPS-induced expression of inflammatory factors. The inhibitory effect of propofol on inflammatory factor expression is likely mediated by the inhibition of p38 activation.

Keyphrases

inflammatory response
lipopolysaccharide induced
lps induced

induced apoptosis
poor prognosis
cell cycle arrest

toll like receptor
oxidative stress
endothelial cells

signaling pathway
cell death