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Green Tea Prevents NAFLD by Modulation of miR-34a and miR-194 Expression in a High-Fat Diet Mouse Model.

L F TorresB CogliatiRosemari Otton
Published in: Oxidative medicine and cellular longevity (2019)
Our study identified for the first time that the beneficial effects of GT in the liver can be due to the modulation of miRNAs, opening new perspectives for the treatment of NAFLD focusing on epigenetic regulation of miR-34a and miR-194 as green tea targets.
Keyphrases
  • cell proliferation
  • long non coding rna
  • high fat diet
  • long noncoding rna
  • mouse model
  • poor prognosis
  • insulin resistance
  • adipose tissue
  • type diabetes
  • skeletal muscle
  • binding protein
  • combination therapy