Administration of human umbilical cord blood mononuclear cells restores bladder dysfunction in streptozotocin-induced diabetic rats.
Ecem Kaya SezginerDidem Yilmaz-OralSerap GurPublished in: Lower urinary tract symptoms (2019)
Administration of HUCB-MNCs facilitates bladder function recovery, which is likely related to downregulation of HIF-1α expression and attenuation of fibrosis in STZ-diabetic rats.
Keyphrases
- diabetic rats
- oxidative stress
- cord blood
- induced apoptosis
- spinal cord injury
- poor prognosis
- cell cycle arrest
- signaling pathway
- urinary tract
- cell proliferation
- peripheral blood
- endoplasmic reticulum stress
- type diabetes
- endothelial cells
- long non coding rna
- high fat diet
- pi k akt
- adipose tissue
- drug induced
- insulin resistance