F13A1 transglutaminase expression in human adipose tissue increases in acquired excess weight and associates with inflammatory status of adipocytes.

Mari T KaartinenM AroraS HeinonenA HangA BarryJ LundbomAntti HakkarainenN LundholmA RissanenJaakko A Kaprio Kirsi H Pietiläinen

Published in: International journal of obesity (2005) (2020)

F13A1 levels in adipose tissue increase with acquired excess weight and associate with pro-inflammatory, cell stress and tissue remodeling pathways. This supports its role in expansion and inflammation of adipose tissue in obesity.

Keyphrases

adipose tissue
insulin resistance
weight loss
weight gain
high fat diet
oxidative stress
body mass index
physical activity
endothelial cells
metabolic syndrome
poor prognosis
high fat diet induced
single cell
type diabetes
cell therapy
skeletal muscle
bone marrow
heat stress