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Ex vivo Anti-Senescence Activity of N-Acetylcysteine in Visceral Adipose Tissue of Obese Volunteers.
Diba Behtaj
Arman Ghorbani
Ghazaleh Eslamian
Nasser Malekpour Alamdari
Maryam Abbasi
Hamid Zand
Azam Shakery
Ghazaleh Shimi
Mohammad Hasan Sohouli
Sepideh Fazeli Taherian
Published in:
Obesity facts (2024)
Taken together, these data suggest the senotherapeutic effect of NAC, as it effectively reduces the activity of SA-β-gal and the expression of IL-6, P16, and P21 genes in the visceral adipose tissue of obese individuals.
Keyphrases
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adipose tissue
insulin resistance
high fat diet
poor prognosis
metabolic syndrome
weight loss
type diabetes
transcription factor
dna damage
genome wide
electronic health record
endothelial cells
big data
gene expression
bariatric surgery
binding protein
dna methylation
oxidative stress
skeletal muscle
deep learning