Impact of lipophilic vs hydrophilic statins on the clinical outcome and biomarkers of remodelling in heart failure patients: A prospective comparative randomized study.
Nouran Omar El SaidLamia Mohamed El WakeelHazem KhorshidEbtissam Abdel Ghaffar DarweeshMarwa Adel AhmedPublished in: British journal of clinical pharmacology (2021)
The study results suggest that lipophilic atorvastatin is superior to hydrophilic rosuvastatin in increasing left ventricular ejection fraction and reducing fibrosis marker sST2 in HF patients. Trial registration ID: NCT03255044, registered on 21 August 2017.
Keyphrases
- ejection fraction
- aortic stenosis
- left ventricular
- liquid chromatography
- cardiovascular disease
- clinical trial
- end stage renal disease
- heart failure
- study protocol
- randomized controlled trial
- acute myocardial infarction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- phase iii
- acute coronary syndrome
- percutaneous coronary intervention
- simultaneous determination